Chie Nishioka Selected Research

Acute Eosinophilic Leukemia

9/2007

AZD1152, a novel and selective aurora B kinase inhibitor, induces growth arrest, apoptosis, and sensitization for tubulin depolymerizing agent or topoisomerase II inhibitor in human acute leukemia cells in vitro and in vivo.

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Chie Nishioka Research Topics

Disease

26	Leukemia 04/2017 - 10/2006
19	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 04/2017 - 06/2007
8	Neoplasms (Cancer) 01/2015 - 09/2006
4	Acute Promyelocytic Leukemia 12/2017 - 11/2011
4	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2017 - 09/2007
3	Blast Crisis (Blast Phase) 03/2014 - 10/2006
3	Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated) 03/2013 - 05/2007
3	Hypereosinophilic Syndrome (Loeffler Endocarditis) 08/2010 - 10/2006
2	Graft vs Host Disease (Graft-Versus-Host Disease) 05/2017 - 06/2008
2	Necrosis 03/2013 - 06/2008
2	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 02/2012 - 09/2006
2	Non-Hodgkin Lymphoma (Lymphosarcoma) 12/2009 - 10/2006
1	Disseminated Intravascular Coagulation 12/2017
1	Sepsis (Septicemia) 01/2017
1	Inflammation (Inflammations) 01/2017
1	Myeloid Leukemia (Leukemia, Myelocytic) 09/2012
1	Acute Myelomonocytic Leukemia 05/2012
1	Breast Neoplasms (Breast Cancer) 08/2010
1	Polyploidy 01/2010
1	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 12/2009
1	B-Cell Lymphoma (Lymphoma, B Cell) 12/2009
1	Acute Biphenotypic Leukemia (Leukemia, Mixed Cell) 06/2008
1	Acute Monocytic Leukemia (Acute Monoblastic Leukemia) 06/2008

Drug/Important Bio-Agent (IBA)

6	ThrombomodulinIBA 12/2017 - 05/2012
6	Proteins (Proteins, Gene)FDA Link 01/2015 - 10/2006
5	Phosphotransferases (Kinase)IBA 03/2014 - 06/2007
5	Everolimus FDA Link 03/2013 - 10/2006
5	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 07/2010 - 06/2008
4	Tretinoin (Retinoic Acid)FDA LinkGeneric 12/2017 - 10/2009
4	Sunitinib (Sutent)FDA Link 02/2012 - 09/2006
4	TOR Serine-Threonine KinasesIBA 08/2010 - 10/2006
4	AZD 6244IBA 07/2010 - 06/2008
3	Epidermal Growth Factor (EGF)IBA 05/2017 - 05/2012
3	Cytarabine (Cytosar-U)FDA LinkGeneric 04/2017 - 09/2009
3	DNA (Deoxyribonucleic Acid)IBA 03/2014 - 06/2007
3	Aurora Kinase AIBA 03/2014 - 06/2007
3	Imatinib Mesylate (Gleevec)FDA Link 02/2012 - 05/2008
3	Aurora Kinase BIBA 01/2010 - 09/2007
2	Small Interfering RNA (siRNA)IBA 04/2017 - 11/2013
2	Interleukin-10 (Interleukin 10)IBA 04/2017 - 03/2013
2	ChromatinIBA 01/2016 - 01/2015
2	Matrix Metalloproteinase 9 (Gelatinase B)IBA 09/2015 - 01/2015
2	Messenger RNA (mRNA)IBA 08/2015 - 01/2015
2	STAT5 Transcription FactorIBA 08/2015 - 05/2011
2	MethyltransferasesIBA 03/2014 - 07/2011
2	Decitabine FDA Link 03/2014 - 07/2011
2	Tyrosine Kinase InhibitorsIBA 03/2014 - 02/2012
2	CytokinesIBA 03/2013 - 06/2008
2	entinostat (MS 275)IBA 07/2011 - 09/2008
2	Mechanistic Target of Rapamycin Complex 1IBA 07/2010 - 10/2009
2	Peptide Initiation Factors (Initiation Factor)IBA 07/2010 - 10/2006
2	Histone Deacetylase InhibitorsIBA 09/2009 - 09/2008
2	Mitogen-Activated Protein KinasesIBA 09/2009 - 09/2009
2	MAP Kinase Kinase Kinases (MAP Kinase Kinase Kinase)IBA 09/2009 - 09/2009
2	fms-Like Tyrosine Kinase 3IBA 09/2008 - 05/2008
2	NF-kappa B (NF-kB)IBA 06/2008 - 02/2008
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 05/2008 - 10/2006
2	ThymidineIBA 09/2007 - 06/2007
2	Aurora KinasesIBA 09/2007 - 06/2007
2	Sirolimus (Rapamycin)FDA Link 05/2007 - 10/2006
1	CoagulantsIBA 12/2017
1	Dacarbazine (DIC)FDA LinkGeneric 12/2017
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 05/2017
1	Cadherins (E-Cadherin)IBA 04/2017
1	DNA Methyltransferase 3AIBA 04/2017
1	bcr-abl Fusion ProteinsIBA 01/2017
1	LipopolysaccharidesIBA 01/2017
1	Monoclonal AntibodiesIBA 09/2015
1	p38 Mitogen-Activated Protein KinasesIBA 01/2015
1	Histones (Histone)IBA 01/2015
1	Lysine (L-Lysine)FDA Link 01/2015
1	Enhancer of Zeste Homolog 2 ProteinIBA 01/2015
1	TetraspaninsIBA 01/2015
1	Dasatinib (BMS 354825)FDA Link 03/2014
1	MLN 8237IBA 03/2014
1	MicroRNAs (MicroRNA)IBA 03/2014
1	Culture MediaIBA 03/2013
1	3- (4- methylphenylsulfonyl)- 2- propenenitrileIBA 03/2013
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 09/2012
1	Calcineurin InhibitorsIBA 09/2012
1	Antifibrinolytic Agents (Antifibrinolytics)IBA 06/2012
1	Protein CIBA 05/2012
1	Janus Kinase 2IBA 11/2011
1	Transcription Factors (Transcription Factor)IBA 07/2011
1	Histone Deacetylases (Histone Deacetylase)IBA 07/2011
1	Janus KinasesIBA 05/2011
1	nilotinib FDA Link 08/2010
1	1,25-dihydroxyvitamin DIBA 08/2010
1	CaspasesIBA 12/2009
1	Protein Kinases (Protein Kinase)IBA 12/2009
1	BromidesIBA 09/2008
1	Protein Isoforms (Isoforms)IBA 06/2008
1	Interleukin-2 (IL2)IBA 06/2008
1	Interferon-gamma (Interferon, gamma)IBA 06/2008
1	Ki11502IBA 05/2008
1	Platelet-Derived Growth Factor alpha ReceptorIBA 05/2008
1	2- ((3- ((4- ((5- (2- ((3- fluorophenyl)amino)- 2- oxoethyl)- 1H- pyrazol- 3- yl)amino)quinazolin- 7- yl)oxy)propyl)(ethyl)amino)ethyl dihydrogen phosphateIBA 09/2007

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 01/2015
1	Therapeutics 08/2010
1	Stem Cell Transplantation 06/2008